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An anthropomorphic organ, and boss of "Intestinal Distress". Although he has a habit of spitting out a deadly bile from his body, he's a rather neat and tidy individual (according to the manual). Doc Duodenum and his level are not in the SNES version of the game. Although he did not appear in the level, "The Villi People" is said to be his summer home in the Earthworm Jim 2 manual.

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